So easy to take Just a habit now each morning
Very nice apron, it is perfect for my gardening needs
| The Fountain of Youth Lifestyle (FoYL) Tripeptide Collagen has been Independently tested by a leading European university using pharmaceutical laboratory models. |
FoYL’s tripeptide collagen has undergone independent, third-party, pharmaceutical laboratory testing by The University of Studies of Milan, to evaluate not just composition, but functional biological performance - something never done before for collagen ingredients.
The independent studies were conducted by:
Università degli Studi di Milano (University of Studies of Milan) – Dipartimento di Scienze Farmaceutiche (Department of Pharmaceutical Sciences) (DiSFaRM)
Final Scientific Report Date: 27 June 2025
Click Here to view a synopsis of the clinical trial results (will open a new window).
Independent laboratory testing demonstrated that FoYL’s tripeptide collagen is fundamentally different from standard or hydrolysed collagen products.
Rather than acting solely as a source of amino acids, FoYL’s ultra-low molecular weight tripeptide collagen was shown to behave as a bioactive peptide system, interacting with key metabolic and vascular pathways under controlled laboratory conditions.
Up to 5× Higher Predicted Bioactivity:
Advanced peptide mapping showed that FoYL’s tripeptide collagen exhibits up to five times greater predicted biological activity compared with conventional collagen peptides.
What this means for you:
More of the collagen you consume is biologically “active”, not just digested and discarded.
Precision Peptides for Superior Absorption:
This size range aligns with the optimal zone for collagen peptide absorption and signalling, allowing peptides to be rapidly absorbed while retaining their functional activity.
What this means for you:
Your body can absorb and use this collagen more efficiently than standard, larger collagen peptides.
Laboratory testing showed that FoYL’s tripeptide collagen:
What this means for you:
Support for metabolic balance — not through stimulants or drugs, but by working with your body’s own signalling systems.
The studies also demonstrated interaction with enzyme systems involved in:
What this means for you:
FoYL collagen supports whole-body wellbeing, not just skin, hair, or joints.
Proven to Remain Active in the Gut:
Importantly, FoYL’s tripeptide collagen retained biological activity in human intestinal cell models (in-situ testing).
Most collagen products are never tested this way of to this level.
What this means for you:
This collagen doesn’t just look good on paper — it remains active where absorption actually occurs.
What this means for you:
Designed for daily use as part of a long-term wellness routine.
Most collagen products rely on:
FoYL’s collagen is supported by independent university-led testing demonstrating:
This positions FoYL collagen as a next-generation, precision-designed collagen, not a commodity protein powder.
The Fountain of Youth Lifestyle Tripeptide Collagen.
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Independent scientific evaluation conducted by: Università degli Studi di Milano (University of Studies of Milan) – Dipartimento di Scienze Farmaceutiche (Department of Pharmaceutical Sciences) (DiSFaRM)
Final report dated 27.06.2025
Please Note: Not all related to Tripeptide Collagen
# |
First author, year (journal) |
Key finding (dose / model) |
Free full-text / DOI |
|---|---|---|---|
| 1 | Inoue 2016 (J Sci Food Agric) | 5 g day⁻¹ “NGI” bovine HC for 8 weeks ↑ skin hydration (+7-12 %), elasticity (+4-9 %), ↓ wrinkle depth (-8 %) in 56 women (DB-RCT). | PubMed: https://pubmed.ncbi.nlm.nih.gov/26840887 Europe PMC |
| 2 | Ohara 2007 (J Agric Food Chem) | Human crossover study (5 ♂) showed plasma peak 20-60 nmol mL⁻¹ Hyp-di/tripeptides 1-2 h after 10 g bovine HC. | https://pubmed.ncbi.nlm.nih.gov/17253720 Europe PMC |
| 3 | Iwai 2005 (J Agric Food Chem) | First identification of food-derived Pro-Hyp in human blood after 10 g porcine/bovine HC; proves intact tripeptide absorption. | https://pubmed.ncbi.nlm.nih.gov/16076145 Europe PMC |
| 4 | Ichikawa 2010 (Int J Food Sci Nutr) | 9 g day⁻¹ bovine HC for 4 weeks: plasma Pro-Hyp 4-fold ↑; confirms dose-dependence of tripeptide appearance. | https://pubmed.ncbi.nlm.nih.gov/19961355 Europe PMC |
| 5 | Watanabe-Kamiyama 2010 (J Agric Food Chem) | Rats given low-MW bovine HC (average 3 kDa): ↑ femoral bone mineral content (+7 %). | https://pubmed.ncbi.nlm.nih.gov/19957932 Europe PMC |
| 6 | Yamamoto 2016 (Biol Pharm Bull) | Human study comparing purified CTP-50 vs generic HC: plasma & urinary Pro-Hyp ↑ proportional to Gly-Pro-Hyp intake. | https://pubmed.ncbi.nlm.nih.gov/26934933 Europe PMC |
| 7 | Proksch 2014 – VERISOL® (Skin Pharmacol Physiol) | 2.5 g bovine-hide BCP for 8 weeks ↓ eye-wrinkle volume by -20 %; procollagen I +65 %. | https://pubmed.ncbi.nlm.nih.gov/24401291 Europe PMC |
| 8 | Proksch 2013 (Skin Pharmacol Physiol) | 2.5 or 5 g bovine HC for 8 weeks ↑ skin elasticity 15 %; effect persisted 4 weeks post-intervention. | https://pubmed.ncbi.nlm.nih.gov/23949208 Europe PMC |
| 9 | Song 2013 (Clin Interv Aging) | 3 g collagen tripeptide for 12 weeks ↑ skin hydration (+28 %) & elasticity (+19 %) in healthy adults. | https://pubmed.ncbi.nlm.nih.gov/24131075 Europe PMC |
| 10 | Hexsel 2017 (J Cosmet Dermatol) | 2.5 g bovine BCP × 24 weeks: ↑ nail growth rate (+12 %) & ↓ fragility (-42 %). | https://pubmed.ncbi.nlm.nih.gov/28786550 Europe PMC |
# |
Study & model |
What they measured |
Direction of the main result |
|---|---|---|---|
| 1 | Inoue 2016 – 8-week DB-RCT, 56 women, 5 g/day bovine HC | Corneometer skin hydration, Cutometer elasticity, fringe-projection wrinkle depth | ↑ Hydration (+7-12 %), ↑ elasticity (+4-9 %), ↓ wrinkle depth (-8 %) vs placebo ndlabs.com |
| 2 | Ohara 2007 – single-dose crossover PK, 5 men, 10 g bovine HC | Plasma levels of Hyp-di/tri-peptides | Peaks of 20-60 nmol mL-¹ Pro-Hyp/Hyp-Gly at 1-2 h post-dose (none at baseline) Europe PMC |
| 3 | Iwai 2005 – single-dose PK, 5 volunteers, 10 g porcine/bovine HC | Identification of intact tripeptides in serum | First proof of Pro-Hyp appearance in human blood after oral collagen (positive mechanistic outcome) skinglow.com.ar |
| 4 | Ichikawa 2010 – dose-escalation PK, 4 volunteers | Dose-response of plasma Hyp-peptides (30–385 mg kg-¹) | Clear, linear ↑ in peptide Cmax with higher doses (6 → 33 nmol mL-¹) Europe PMC |
| 5 | Watanabe-Kamiyama 2010 – ovariectomised-rat model, 4 wks LMW bovine HC | Femoral bone organic content & BMC | ↑ Bone organic matter and BMC (+7 %) vs controls; protective against osteoporosis Medscape |
| 6 | Yamamoto 2016 – human crossover, 9 subjects, tripeptide-enriched CTP vs generic HC | Plasma & urinary Gly-Pro-Hyp/Pro-Hyp | Higher and longer-lasting peptide levels with CTP-50; magnitude proportional to tripeptide dose JSTAGE |
| 7 | Proksch 2014 – 114 women, 2.5 g VERISOL® for 8 wks | 3-D stereo wrinkle volume & dermal biopsies | -20 % eye-wrinkle volume; +65 % procollagen-I vs placebo (p < 0.05) Europe PMC |
| 8 | Proksch 2013 – 69 women, 2.5 / 5 g collagen peptides for 8 wks | Cutometer elasticity (R2) | +15 % elasticity at both doses; effect persisted 4 wks after stopping Europe PMC |
| 9 | Song 2013 (Kim BJ) – 64 adults, 3 g collagen tripeptide 12 wks | Hydration & elasticity vs control | +28 % hydration, +19 % elasticity; both significant vs control Europe PMC |
| 10 | Hexsel 2017 – 25 women, 2.5 g VERISOL® 24 wks (open-label) | Nail growth rate & brittleness | +12 % growth rate, -42 % cracked/brittle nails; 64 % “overall improvement” by physician assessment Europe PMC |